Regarding pharmacological interventions for alcohol use disorders, recent laboratory studies of naltrexone have elucidated its mechanisms of action. Importantly, one study examined the effects of naltrexone on alcohol non-abstainers and found that participants who drank regularly during the treatment period benefited more from naltrexone relative to placebo (Ray, Krull, & Leggio, 2010). Together, these findings […]

“Some people think of the effects of alcohol as only something to be worried about if you’re living with alcohol use disorder, which was formerly called alcoholism,” Dr. Sengupta says. Alcohol may affect various mechanisms implicated in ischemic preconditioning. Among these is the activation of mitogen-activated protein kinases (MAPK) signaling cascades. Long-Term Effects Of Alcohol […]